ea0085oc8.1 | Oral Communications 8 | BSPED2022
Kaninde Abhidhamma
, Kuo Michael
, Ren Ong Kai
, Barrett Timothy
, Dias Renuka
Background: Germline mutations in the Phosphatase and Tensin Homolog Hamartoma tumour (PTEN) gene are associated with a number of conditions, collectively known as PTEN hamartoma tumour syndromes (PHTS). Individuals with PHTS are at increased risk of a number of cancers primarily in adulthood including differentiated thyroid carcinoma (DTC) with an estimated lifetime risk of DTC of up to 38%. International guidance recommends screening commencing from 17 years while the 2017-U...